Molecular Cytogenetics: Protocols and Applications
نویسندگان
چکیده
منابع مشابه
Molecular cytogenetics: recent developments and applications in cancer.
Aneuploidy or alteration in chromosome numbers is a characteristic feature in cancer that is generally a consequence of defective chromosome segregation during cell division. Molecular cytogenetic analyses have conferred substantial evidence with regards to the chromosomal architectures in cancer. Most importantly, the fluorescence in situ hybridization (FISH) technique that plays a leading rol...
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Chronic Myeloid Leukemia (CML) is a hematopoietic malignancy characterized by the presence ofPhiladelphia (Ph1) chromosome that results from balanced reciprocal translocation between chromosomes9 and 22 leading in the formation of bcr/abl fusion gene. The present study was conducted to evaluate cytogenetic and molecular abnormalities in CML patients at presentation and during the co...
متن کاملComparative Molecular Cytogenetics and Chromosome Evolution
ABC Fax + 41 61 306 12 34 E-mail [email protected] www.karger.com © 2005 S. Karger AG, Basel 0301–0171/05/1083–0139$22.00/0 Accessible online at: www.karger.com/cgr Abstract. For the last 15 years molecular cytogenetic techniques have been extensively used to study primate evolution. Molecular probes were helpful to distinguish mammalian chromosomes and chromosome segments on the basis of their ...
متن کاملComparative Molecular Cytogenetics and Chromosome Evolution
ABC Fax + 41 61 306 12 34 E-mail [email protected] www.karger.com © 2005 S. Karger AG, Basel 0301–0171/05/1083–0191$22.00/0 Accessible online at: www.karger.com/cgr Abstract. We report on the cytogenetics of twin offspring from an interspecies cross in marmosets (Callitrichinae, Platyrrhini), resulting from a pairing between a female Common marmoset (Callithrix jacchus, 2n = 46) and a male Pygmy...
متن کاملMolecular Cytogenetics and Cytogenomics of Brain Diseases
Molecular cytogenetics is a promising field of biomedical research that has recently revolutionized our thinking on genome structure and behavior. This is in part due to discoveries of human genomic variations and their contribution to biodiversity and disease. Since these studies were primarily targeted at variation of the genome structure, it appears apposite to cover them by molecular cytoge...
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ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 2003
ISSN: 0002-9297
DOI: 10.1086/375142